Chloroquine, Hydroxychloroquine and Covid-19: a systematic review of literature

Authors

  • Jose Paulo Guida Sao Leopoldo Mandic

DOI:

https://doi.org/10.31005/iajmh.v3i0.79

Keywords:

hydroxychloroquine, COVID-19

Abstract

Objective: to assess effectiveness and safety of hydroxychloroquine and chloroquine on the treatment of COVID-19. Study desing: a systematic review of literature was performed in two databases; studies were included if they had as intervention use of chloroquine or hydroxychloroquine and reported outcomes on laboratorial or clinical findings or description of side effects. Results: 38 studies were included; of those, only one fulfilled inclusion criteria and were included in this review. This study has important methodological issues and only reported viral load, but any clinical outcomes. Conclusions: Many ongoing clinical trials will provide new evidences about the use of hydroxychloroquine and chloroquine to the treatment of COVID-19. Current evidence do not support its use on clinical practice.

Published

2020-04-02

How to Cite

Guida, J. P. (2020). Chloroquine, Hydroxychloroquine and Covid-19: a systematic review of literature. InterAmerican Journal of Medicine and Health, 3, 1–10. https://doi.org/10.31005/iajmh.v3i0.79

Issue

Section

Review Articles